Vitamin D And Diseases

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Vitamin D deficiency appears to be related to the development of RA and correlates with disease severity. - A higher risk of diabetes and heart disease.


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Vitamin D deficiency is related to various autoimmune disorders.

Vitamin d and diseases. This study of more than 25000 older adults in the US. Vitamin D deficiency has been. Vitamin D and Chronic Diseases Aging Dis.

Association between low levels of serum 25-hydroxyvitamin D and increased risk of developing several immune-related diseases and disorders including psoriasis type 1 diabetes multiple sclerosis rheumatoid arthritis tuberculosis sepsis respiratory infection and COVID-19 has been observed. Vitamin D deficiency remains a worldwide public health problem affecting large proportions of the population in developed and the developing countries. Vitamin D3 or cholecalciferol can be produced in adequate amounts by skin exposure to sunlight.

125 OH 2 D was well-documented to be a very effective hormone in inhibiting proliferation and inducing terminal differentiation of a wide variety of cultured malignant cells including prostate cancer colon cancer breast cancer and leukemic cells 2. 3 however vitamin D vitD insufficiency remains common. Following is a very brief review of some of the chronic disorders in which vitamin D deficiency has been found to play a role either from epidemiologic studies or from randomized controlled trials of vitamin D intervention.

Many people hope to protect themselves from various diseases by taking vitamin D including Covid-19. Moreover chronic inflammatory diseases such as atherosclerosis-related cardiovascular disease asthma inflammatory bowel disease chronic kidney disease nonalcoholic fatty liver disease and others tend to have lower vitamin D status which may play a pleiotropic role in the pathogenesis of the diseases. Vitamin D was discovered early in the 20th century as the component of fish oil essential for the prevention and cure of rachitic bone disease.

Vitamin D deficiency is associated with vascular dysfunction arterial stiffening left ventricular hypertrophy and hyperlipidemia. As a member of the steroid hormone family it has a classic role in regulating metabolism of calcium and a non-classic role in affecting cell proliferation and differentiation. In this regard either observational studies aimed to verify an association between low vitamin D level and the.

But things are not that simple. Published in The BMJ reports that vitamin D supplementation over a period of 5 years reduced autoimmune diseases by 22 percent. However immune genetic and environmental factors are thought to be involved.

For these reasons vitamin D. Vitamin D VD is a fat-soluble steroid essential for life in higher animals. According to recent studies vitamin D deficiency is likely to be an important etiological factor in the pathogenesis of many chronic diseases as well as it has been associated with higher mortality rate for respiratory disease.

Vitamin D and Chronic Disease. The prevalence of vitamin D deficiency is higher in diabetic or obese children and patients with thyroiditis compared to healthy controls. 12 Maintaining adequate serum 25-hydroxyvitamin D 25OHD status has an established role in CD for bone health.

Vitamin D Deficiency and Heart Disease. A lack of vitamin D has been linked to autoimmune diseases including type 1 diabetes autoimmune thyroiditis and to obesity. Cardiovascular disease Vitamin D helps regulate the renin-angiotensin-aldosterone system and thereby blood pressure vascular cell growth and inflammatory and fibrotic pathways.

Vitamin D2 or ergocalciferol a related compound with very similar activities is found in a few plants. Vitamin D is one of the essential nutrients to sustain the human health. Moreover low vitamin D values seem to be associated with major complications and.

Here vitamin D physiology and metabolism its genomic action and association of polymorphisms in vitamin D pathway genes with different diseases are reviewed by focusing on new findings published. Vitamin D and Immune-Related Diseases. A lack of Vitamin D can also lead to.

VD is primarily produced in the skin by the direct action of ultraviolet UV sunlight with a much smaller proportion coming from dietary intake The two major forms of VD are ergocalciferol VD 2 and cholecalciferol VD 3VD 2 is most commonly added to foods given. In a new study investigators from Brigham and Womens Hospital found the people who took vitamin D or vitamin D and omega-3 fatty acids had a significantly lower rate of autoimmune diseases such as rheumatoid arthritis polymyalgia rheumatica autoimmune thyroid disease and psoriasis than people who took a placebo. In fact countless studies have shown such connections.

-Rickets a disease that causes soft and weak bones in children -Osteoporosis a disease that causes bones to become thin and brittle -Heart disease. -A weakened immune system. Heart health Vitamin D deficiency may be linked to a higher risk of high blood pressure hypertension as well as increased risk of death from cardiovascular disease.

With their findings published. Inflammation It has been found that vitamin D deficiency is associated with inflammation a negative response of the immune system. Vitamin D deficiency is an increasingly described phenomenon worldwide Compelling evidence from human disease associations and basic physiological studies demonstrated the significance of vitamin D deficiency in various physiological disorders including neuropathy malignancy 3 4 infertility cardiovascular diseases 6 7 kidney.

The aetiology is unknown. Vitamin D deficiency is observed in patients with SLE. It was found to be related to disease severity and activity in some but not all studies.

- Poor dental health. Accordingly a number of clinical trials aiming. 456 In Europe CD incidence rates range from 07 to 98 cases per.

Despite the numerous reports of the association of vitamin D with a spectrum of development disease treatment and health maintenance vitamin D deficiency is common. Numerous studies have shown an association between low vitamin D blood levels and heart. Originating in part from the diet but with a key source resulting from transformation by exposure to sunshine a great deal of the population suffers from vitamin D deficiency especially during.


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